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Home » Products » Anti-allergic/Anti-Cold » Deflazacort 6 mg Tablet

Deflazacort 6 mg Tablet

Deflazacort 6 mg Tablet
Deflazacort 6 mg Tablet
Product Code : 024256
Brand Name : Zoydef
Product Description

Each tablet contains Deflazacort 6 mg 

Brand Name: Zoydef 

Pack: 1x10 

Deflazacort is a glucocorticoid used as an anti-inflammatory and immunosuppressant. Deflazacort is a prodrug. Its potency is around 70-90% that of prednisone.

Pharmacokinetics

  • Deflazacort, derived from prednisolone, is a corticosteroid with mainly glucocorticoid activity. An anti-inflammatory dose of 6 mg deflazacort is equiv to 5 mg prednisolone.

Deflazacort Adverse Reactions / Deflazacort Side Effects

  • GI disturbances, musculoskeletal, endocrine, neuropsychiatric, ophthalmic, fluid and electrolyte disturbances; susceptible to infection, impaired healing, hypersensitivity, skin atrophy, striae, telangiectasia, acne, myocardial rupture following recent MI, thromboembolism.

Special Precautions

  • Adrenal suppression and infection, child, adolescents, elderly, history of TB and steroid myopathy, hypertension, recent MI, CHF, liver failure, renal impairment, DM and glaucoma (including family history), osteoporosis, corneal perforation, severe affective disorders, epilepsy, peptic ulcer, hypothyroidism, pregnancy and lactation.

Other Drug Interactions

  • Antacids, ACE inhibitors, acetazolamide, adrenergic neuron blockers, antidiabetics, calcium-channel blockers, carbamazepine, carbenoxolone, cardiac glycosides, clonidine, coumarins, diazoxide, diuretics, erythromycin, hydralazine, ketoconazole, methotrexate, methyldopa, mifepristone, minoxidil, moxonidine, nitrates, nitroprusside, NSAIDs, oestrogens, phenytoin, primidone, rifamycins, ritonavir, somatropin, 2 sympathomimetics, theophylline, vaccines.

Other Interactions

  • Food Interaction: Salad and vegetable diet including alcohol may affect anticoagulant control.

Dosage

  • Oral Allergic and inflammatory disorders Adult: Initially, up to 120 mg daily. Maintenance: 3-18 mg/day. Child: 0.25-1.5 mg/kg/day given on alternate days. Hepatic impairment: Dose reductions may be needed.

List of Contraindications

  • Deflazacort and Pregnancy: Caution when used during pregnancy

  • Deflazacort and Lactation: Caution when used during lactation





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